Includes bibliographical references (pages 446-515) and index.

Physical Description: print xii, 535 pages : illustrations 24 cm.

The drug went on to generate some thirty-five billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die. The template Arthur Sackler created to sell Valium-co-opting doctors, influencing the FDA, downplaying the drug's addictiveness-was employed to launch a far more potent product: Ox圜ontin. Forty years later, Raymond's son Richard ran the family-owned Purdue. Their children and grandchildren grew up in luxury. The brothers began collecting art, and wives, and grand residences in exotic locales. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. Arthur devised the marketing for Valium, and built the first great Sackler fortune. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments.

Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism.

The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The Sackler name adorns the walls of many storied institutions-Harvard, the Metropolitan Museum of Art, Oxford, the Louvre.

Empire of pain audio book